KMID : 1132720040020040163
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Genomics & Informatics 2004 Volume.2 No. 4 p.163 ~ p.166
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Comparative Study of Human and Chimpanzee Genome
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Choi Sang-Hang
Kim Dae-Soo Kim Dae-Won Lee Yong-Seok Park Hong-Seog
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Abstract
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Chimpanzee is an essential organism in the earth to understand the human unique features, such as highly developed cognitive functions, bipedalism and the use of complex language. Therefore, a number of pilot studies comparing the human and chimpanzee genome have been conducted to understand the genetic basis of the unique features of humans, although all of their studies are by using partial genome information (Park et al., 2000; King et al., 1975; Fujiyama et al., 2002; Olson et al., 2003; Boffelli et al., 2003). The recently released human genome sequences provide us with reference data to conduct comparative genomic research between human and chimpanzee. One of pioneer group in this field is
¡°The International Chimpanzee Genome Sequencing Consortium.¡± The consortium was organized by 8 centers from 5 countries at 13 March 2001 (Table 1). This is a review article of comparative genome analysis between human and chimpanzee which have been conducted by the consortium.
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KEYWORD
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human and chimpanzee genome, comparative genomics, evdution, phsical map, sequencing
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